Prenatal genistein in soy may reduce obesity in offspring


Dated: 29 March 2006

A single nutrient found in soy products elicits changes in gene behavior that permanently reduce an embryo's risk of becoming obese later in life, according to an animal study at Duke University Medical Center.

The findings, yet to be confirmed in humans, could explain why Asians have lower rates of obesity and cancer, says the Duke researchers. Asians consume large amounts of soy, which has been linked to lower rates of breast, endometrial and prostate cancer, among other health benefits.

Results of the study, funded by the National Institute of Environmental Health Sciences and the National Cancer Institute, are published in the April 1, 2006, issue of the journal Environmental Health Perspectives.

"We are increasingly finding that our parent's and even our grandparent's nutritional status and environmental exposures can regulate our future risk of disease," explains Randy Jirtle, PhD, professor of radiation oncology and senior author of the study. "In other words, it may not only be the hamburgers and fries we are eating, but also what our parents consumed or encountered in the environment that predisposes us to various conditions."

Prenatal genistein in soy may reduce obesity in offspring

 
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